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CAS NO:
34580-14-8
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Basic Info
CAS Number
34580-14-8
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Ketotifen is a widely utilized pharmaceutical agent belonging to the class of second-generation antihistamines and mast cell stabilizers. Its chemical identity is defined by the molecular formula C19H20ClNO, with the corresponding CAS registry number 29825-44-7. Structurally, it features a tricyclic framework that distinguishes it from many other antihistamines, contributing to its unique dual mechanism of action in clinical settings. The primary therapeutic application of Ketotifen lies in the management of allergic conditions, particularly allergic conjunctivitis and bronchial asthma. As an ophthalmic solution, it effectively relieves symptoms such as itching, redness, and watering of the eyes caused by seasonal or perennial allergens. When administered orally, often in tablet form, it serves as a prophylactic treatment for asthma, helping to prevent bronchospasm rather than treating acute attacks directly.
The drug works through two distinct pathways: it competitively blocks H1 histamine receptors to mitigate immediate allergic reactions, and simultaneously inhibits the release of inflammatory mediators like histamine and leukotrienes from mast cells. This stabilizing effect makes it particularly valuable for long-term management of chronic allergic diseases. While generally well-tolerated, common side effects include drowsiness, dry mouth, and weight gain, which are characteristic of first-generation antihistamines despite its classification. It is frequently prescribed for patients who do not respond adequately to standard antihistamines alone. In various regions, Ketotifen is available both as a prescription medication and over-the-counter depending on local regulations and formulation strength. Its versatility extends beyond respiratory and ocular allergies, occasionally being explored for other atopic disorders. Overall, Ketotifen remains a cornerstone therapy in allergy management due to its efficacy in preventing symptoms and improving quality of life for millions of patients worldwide suffering from hypersensitivity reactions.
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