*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>J&K Val-Cit-PAB-OH (98%) is a cleavable linker for Antibody-Drug Conjugates (ADCs). It utilizes a valine-citrulline dipeptide sequence recognized by lysosomal enzymes. The compound features a para-aminobenzyl alcohol moiety, enabling efficient drug attachment. <strong>Molecular Formula</strong>: C<sub>24</sub>H<sub>31</sub>N<sub>5</sub>O<sub>6</sub>. <strong>CAS No.</strong>: 170595-67-0.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D</strong>: Synthesis of next-generation ADCs targeting oncology indications.</li>
<li><strong>Medicinal Chemistry</strong>: Platform for developing enzyme-sensitive prodrugs and bioconjugates.</li>
<li><strong>Diagnostic Tools</strong>: Construction of targeted imaging agents via stable covalent bonding.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent hydrolysis. Handle with standard PPE; avoid inhalation or skin contact. Not intended for direct clinical administration without formulation into approved therapeutic conjugates.</p>