【产品名称】:苹果酸舒尼替尼
【Product Name】:Sunitinib malate, 98%, a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively
【产品规格】:一种多靶点受体酪氨酸激酶抑制剂, 抑制VEGFR2和 PDGFRβ的IC50分别为80 nM和2 nM
【CAS】:341031-54-7
【MP】:185-192℃
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sunitinib malate is a multi-targeted receptor tyrosine kinase inhibitor. Its molecular formula is C<sub>22</sub>H<sub>27</sub>F<sub>3</sub>N<sub>4</sub>O<sub>5</sub> and CAS number is 398635-18-0. The compound exhibits potent inhibition with IC<sub>50</sub> values around 80 nM.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology Research:</strong> Preclinical studies targeting renal cell carcinoma and gastrointestinal stromal tumors.</li>
<li><strong>Drug Discovery:</strong> High-purity standard for screening assays and mechanism validation.</li>
<li><strong>Clinical Trials:</strong> Active pharmaceutical ingredient (API) supply for Phase I/II investigations.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to maintain stability. Handle in fume hoods using appropriate PPE due to potential toxicity. Strictly adhere to local regulations regarding hazardous chemical handling and waste disposal.</p>