【产品名称】:奈拉滨
【Product Name】:Nelarabine, 98%, a purine nucleoside analog and DNA synthesis inhibitor
【产品规格】:是嘌呤核苷酸类似物, 为DNA合成抑制剂
【CAS】:121032-29-9
【Storage】:Freezer -20℃
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Nelarabine is a <strong>purine nucleoside analog</strong> and <strong>DNA synthesis inhibitor</strong> marketed by J&K (98% purity). It functions as a prodrug converted intracellularly to the active metabolite Ara-AMP. The chemical formula is <strong>C10H13N5O4</strong> with CAS No. <strong>126470-08-6</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology Research:</strong> Targeting T-cell acute lymphoblastic leukemia (T-ALL) in clinical trials.</li>
<li><strong>Pharmaceutical Manufacturing:</strong> Active Pharmaceutical Ingredient (API) for anti-neoplastic formulations.</li>
<li><strong>Biochemical Studies:</strong> Mechanism validation of DNA replication inhibition pathways.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly store at -20°C under inert atmosphere. Handling requires PPE due to cytotoxicity; avoid inhalation or skin contact. Use only in licensed pharmaceutical facilities.</p>