*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>N-Methyl-D-glucamine</strong> (NMG) is a non-toxic organic base derived from glucose, widely used as a buffering agent and solubilizer in pharmaceutical synthesis. Its primary industrial process involves the reaction of D-glucose with methylamine. Molecular formula: C<sub>7</sub>H<sub>17</sub>NO<sub>5</sub>; CAS No.: 6284-40-8.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Acts as a counterion for acidic drugs to enhance water solubility and bioavailability.</li>
<li><strong>Contrast Media:</strong> Essential component in iodinated X-ray contrast agents.</li>
<li><strong>Chemical Synthesis:</strong> Utilized as an organocatalyst or chiral auxiliary in asymmetric synthesis.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place under inert atmosphere to prevent degradation. While generally safe, avoid inhalation of dust; use appropriate PPE including gloves and eye protection during handling.</p>