【产品名称】:拉帕替尼
【Product Name】:Lapatinib, 98%, a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively
【产品规格】:一种ErbB-2和EGFR酪氨酸激酶结构域的有效抑制剂, 对纯化的EGFR和ErbB-2的IC50值分别为10.2和9.8 nM
【CAS】:231277-92-2
【MP】:137-139℃
【Storage】:Freezer -20℃
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Lapatinib (CAS 231277-92-2) is a potent, reversible dual tyrosine kinase inhibitor targeting <strong>ErbB-2</strong> and <strong>EGFR</strong>. Synthesized via advanced organic coupling, its molecular formula is C<sub>26</sub>H<sub>20</sub>ClFN<sub>4</sub>O<sub>3</sub>, with purity exceeding 98% for research grade.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology Research:</strong> Investigating HER2-positive breast cancer mechanisms.</li>
<li><strong>Drug Development:</strong> Screening candidate compounds for kinase inhibition profiles.</li>
<li><strong>Academic Studies:</strong> Validating ErbB pathway signaling in vitro assays.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C. Strictly for laboratory use only; not approved for clinical administration. Handle with appropriate PPE to prevent inhalation or skin contact.</p>