*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>J&K 4-Maleimidobutyric acid N-hydroxysuccinimide ester (98%) is a heterobifunctional crosslinker. It reacts with sulfhydryl groups to form stable thioether bonds. <strong>Molecular Formula</strong>: C13H14N2O5. <strong>CAS No.</strong>: 6750-73-2.</p>
<h3>Application</h3>
<ul>
<li><strong>Antibody-Drug Conjugates (ADCs)</strong>: Conjugating maleimide-linkers to cysteine residues on therapeutic antibodies.</li>
<li><strong>Bioconjugation</strong>: Attaching fluorescent dyes or biotin to proteins for imaging and assays.</li>
<li><strong>Protein Modification</strong>: Site-specific labeling of enzymes and receptors in biochemical research.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent hydrolysis. Avoid contact with skin and eyes; use appropriate PPE. Not intended for direct clinical administration without formulation.</p>