*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>DOTA is a macrocyclic chelating agent used for radiometal complexation. Its <strong>molecular formula</strong> is C<sub>16</sub>H<sub>28</sub>N<sub>4</sub>O<sub>8</sub> with <strong>CAS No.</strong> 5780-22-5. High purity grades are synthesized via cyclization and acetylation.</p>
<h3>Application</h3>
<ul>
<li><strong>Medical Imaging:</strong> Chelating gadolinium or indium for MRI and PET tracers.</li>
<li><strong>Radiopharmaceuticals:</strong> Targeted alpha therapy using actinium-225.</li>
<li><strong>Research:</strong> Development of stable metal complexes for bioconjugation.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place away from light. Avoid inhalation; wear appropriate PPE during handling. Not approved for direct clinical use without formulation.</p>