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CAS NO:
26675-46-7
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ChP,
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Basic Info
CAS Number
26675-46-7
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Isoflurane, chemically known as 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, is a widely used volatile anesthetic agent in modern medical practice. Its molecular formula is C3H2ClF5O, and it carries the CAS Registry Number 26675-46-7. This clear, colorless liquid possesses a distinct, non-flammable odor and is characterized by its low blood-gas partition coefficient, which facilitates rapid induction and emergence from general anesthesia.
Primarily utilized for the maintenance of general anesthesia in both adults and pediatric patients, Isoflurane acts on the central nervous system to produce unconsciousness, amnesia, and immobility during surgical procedures. It is often administered via inhalation using specialized vaporizers connected to anesthesia delivery systems, sometimes in combination with oxygen and nitrous oxide. One of the most significant advantages of Isoflurane over earlier agents like halothane is its improved safety profile regarding cardiac arrhythmias and hepatic toxicity. It causes minimal myocardial depression and maintains stable cardiovascular function even at higher concentrations, making it particularly suitable for patients with compromised heart conditions. Furthermore, Isoflurane exhibits potent bronchodilatory properties, offering benefits for asthmatic patients undergoing surgery.
The drug is metabolized only minimally by the liver, with less than 2% of the dose undergoing biotransformation into trifluoroacetic acid, thereby reducing the risk of organ damage upon repeated exposure. Its chemical stability ensures compatibility with standard anesthesia circuits without generating harmful byproducts under normal usage conditions. While rare cases of malignant hyperthermia have been reported, Isoflurane remains a cornerstone in anesthesiology due to its predictable pharmacokinetics, ease of titration, and cost-effectiveness. It is available globally as a sterile solution for inhalation, packaged in glass or plastic containers to prevent degradation. As surgical techniques evolve, Isoflurane continues to be a reliable choice for providing safe and effective anesthesia across diverse clinical settings, balancing efficacy with a favorable side-effect profile for both short-term and prolonged procedures.
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