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<h3>Overview</h3>
<p>Irbesartan is a non-peptide <strong>angiotensin II receptor blocker (ARB)</strong> used primarily for hypertension. Synthesized via chiral resolution and coupling reactions, its molecular formula is <strong>C25H28N6O</strong> with CAS No. 138402-77-4.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Bulk production of antihypertensive tablets and fixed-dose combinations.</li>
<li><strong>Clinical Therapy:</strong> Treatment of essential hypertension and diabetic nephropathy in chronic kidney disease patients.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy due to fetal toxicity. Store in a cool, dry place below 25°C protected from light. Personnel must wear appropriate PPE to prevent inhalation or skin contact during handling.</p>