Category:
Finished Dosage
CAS NO:
53-86-1
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Basic Info
Is Manufacturer
YES
Samples Provided
NO
Packaging & Delivery
Packaging Specification
Box of 10 blisters x 10 capsules
Product Description
1.Product name: Indometacin Capsule
2.Specification: 25mg
3.Package: Box of 10 blisters x 10 capsules
4.Shelf life: 36 months
5.Registration documents are available.
If you are interested in our products,please feel free to contact us
AI Product Description
*The following content is generated by AI and is for reference only.
Indomethacin Capsules are a potent nonsteroidal anti-inflammatory drug (NSAID) primarily prescribed to manage pain, inflammation, and stiffness associated with various rheumatic conditions. This medication works by inhibiting the production of prostaglandins, natural substances in the body that trigger fever, pain, and inflammatory responses. Clinically, it is frequently utilized for treating active stages of ankylosing spondylitis, acute gouty arthritis, bursitis, tendonitis, and moderate osteoarthritis. Additionally, it plays a critical role in closing a patent ductus arteriosus in premature infants, though this application typically involves intravenous or rectal formulations rather than oral capsules.
Despite its efficacy, Indomethacin carries significant risks and requires strict medical supervision. The most common adverse effects involve gastrointestinal disturbances, including dyspepsia, nausea, abdominal pain, and a heightened risk of peptic ulcers or gastrointestinal bleeding. Patients must be vigilant for signs of stomach distress, such as black stools or severe heartburn. Cardiovascular risks are also elevated, particularly with long-term use, potentially increasing the likelihood of heart attack or stroke. Consequently, individuals with a history of ischemic heart disease, hypertension, or heart failure should exercise extreme caution.
Contraindications include patients allergic to aspirin or other NSAIDs, those in the third trimester of pregnancy due to the risk of premature closure of the fetal ductus arteriosus, and individuals with active peptic ulcer disease. Renal impairment and severe liver dysfunction also necessitate dose adjustments or avoidance. Elderly patients are at higher risk for serious complications and require careful monitoring. It is crucial to take these capsules with food or milk to minimize gastric irritation and avoid alcohol consumption, which exacerbates stomach bleeding risks. Patients should never discontinue the medication abruptly without consulting their healthcare provider. Regular check-ups to monitor blood pressure, kidney function, and blood counts are essential during therapy. Always follow the prescribed dosage strictly to balance therapeutic benefits against potential systemic toxicity.
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