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Basic Info
Pharmacopoeia
JP
Grade
Food Grade
Is Manufacturer
YES
Product Description
What Are Glutamic Acid?
Glutamic Acid Powder, whose chemical name is α-aminoglutaric acid, is an organic compound with the chemical formula C5H9NO4, which is an acidic amino acid. The molecule contains two carboxyl groups. Glutamic acid was discovered by Lissouson in 1856. It is a colorless crystal with an umami taste. It is slightly soluble in water and soluble in hydrochloric acid solution. Its isoelectric point is 3.22. Glutamic acid is found in large amounts in cereal proteins and is also abundant in animal brains. Glutamic acid plays an important role in protein metabolism in organisms and participates in many important chemical reactions in animals, plants and microorganisms. MSG contains a small amount of glutamic acid.
Physical And Chemical Properties
Glutamic acid is an acidic amino acid. The molecule contains two carboxyl groups, and its chemical name is α-aminoglutaric acid. Glutamic acid was discovered by Lissouson in 1856. It is a colorless crystal with an umami taste. It is slightly soluble in water and soluble in hydrochloric acid solution. Its isoelectric point is 3.22. It is found in large amounts in cereal proteins and is also abundant in animal brains. Glutamic acid plays an important role in protein metabolism in organisms and participates in many important chemical reactions in animals, plants and microorganisms. MSG contains a small amount of glutamic acid.
Glutamic acid (2-aminoglutarate) has left-handed, right-handed and racemic forms. The left-handed body is L-glutamic acid. L-Glutamic acid is a scaly or powdery crystal that is slightly acidic and non-toxic. Slightly soluble in cold water, easily soluble in hot water, almost insoluble in ether, acetone, ethanol and methanol. It sublimates at 200℃ and decomposes at 247℃-249℃. The density is 1.538g/cm3 and the optical rotation is +37~+38.9 (25℃). L-glutamic acid has a wide range of uses. As a medicine, it can treat hepatic coma. It can also be used to produce MSG, food additives, spices and for biochemical research.
Product Details List
| CAS | 56-86-0 |
| Molecular formula | C5H9NO4 |
| Molecular weight | 147.13 |
| EINECS | 200-293-7 |
| Melting point | 205°C(dec.)(lit.) |
| Boiling point | 267.21°C (roughestimate) |
| Specific rotation | 32º(c=10,2NHCl) |
| Density | 1.54g/cm3at20°C |
| Refractive index | 1.4300(estimate) |
| FEMA | 3285|L-GLUTAMICACID |
| Storage conditions | 2-8°C |
| Solubility | 1MHCl:100mg/mL |
| Acidity coefficient (pKa) | 2.13 (at25℃) |
The Significance Of Amino Acid Metabolism
1. Glutamic acid participates in the joint deamination centered on glutamate dehydrogenase (glutamic acid is deaminated).
2. In blood ammonia transport, glutamine synthetase catalyzes the combination of glutamate and ammonia to form glutamine. Glutamine is neutral and non-toxic, easily permeable through cell membranes, and is the main transport form of ammonia.
3. In the glucose-alanine cycle pathway, glutamate dehydrogenase in muscle catalyzes the combination of α-ketoglutarate and ammonia to form glutamate, which is then combined with glutamate under the catalysis of alanine aminotransferase. Pyruvate forms α-ketoglutarate and alanine.
4. In the metabolic pathway of biologically active substances, glutamate itself is an excitatory neurotransmitter and is widely present in the brain and spinal cord. Gamma-aminobutyric acid formed by decarboxylation of glutamic acid is an inhibitory neurotransmitter and is widely used in biology. Widely present in the body.
5. In the amino acid synthesis pathway, glutamic acid is an important precursor for the synthesis of glutamine, proline, arginine, and lysine.
6. In the ornithine cycle (urea synthesis) pathway, glutamate dehydrogenase in the mitochondria removes the amino group of glutamate to provide free ammonia for the synthesis of carbamoyl phosphate; aspartate aminotransferase in the cytoplasm The amino group of glutamic acid is transferred to oxaloacetate, which then forms aspartate and enters the ornithine cycle. Glutamic acid indirectly provides the second amino group for the cycle.
What Are The Benefits?
Protein Synthesis: Glutamic acid powder is one of the amino acid metabolites of methionine and glycine, which is an important component of protein synthesis in the body. During the protein synthesis process, glutamic acid can be converted into glutamine and participate in the formation of polypeptide chains, thus synthesizing various necessary proteins to maintain the body's normal growth and repair tissues.
Energy Metabolism: Plays an important role in the tricarboxylic acid cycle. It can be converted into α-ketoglutarate, which produces adenosine triphosphate (ATP) through the tricarboxylic acid cycle to provide energy for the body. This makes glutamate play an integral role in maintaining the body's normal metabolic activity and providing energy.
Neurotransmitter: one of the precursors of excitatory neurotransmitters in the central nervous system. It participates in the glutamate-glutamate (Glu-Gln) cycle, transmits excitatory signals between synapses by exchanging with glutamate transporters, and is important in maintaining the normal function of the nervous system and learning and memory processes. effect.
Amino Acid Metabolism: It plays an important role in amino acid metabolism. It is a key substance in the amino acid transport process and plays an important role in regulating the amino acid balance in the body. In addition, in the urea cycle, glutamate is also involved in the metabolism and detoxification of amino acids, helping to eliminate amino groups in the body.
Apoptosis Regulation: Research shows that glutamate plays an important role in apoptosis (programmed cell death). It participates in the regulation of apoptosis pathways and plays an important role in maintaining cellular homeostasis and cell self-regulatory mechanisms.
Regulation Of Brain Metabolism: It is also involved in the regulation of neuronal metabolism, including energy metabolism in the brain, regulation of neuronal excitability, etc., and is of great significance to maintaining brain function and normal activity of neurons.
Regulate Acid-Base Balance: Together with other amino acids, it participates in the regulation of acid-base balance in body fluids and maintains the stability of the internal and external environments of cells.
Antioxidant Effect: It also has a certain antioxidant effect, which can help remove free radicals and protect cells from oxidative damage.
Liver Detoxification: It is a key substance in the urea cycle. It participates in the amino acid metabolism and detoxification process, helps the liver eliminate amino groups in the body, and maintains the normal function of the liver.
What Are The Application Directions?
Medically, glutamic acid powder is mainly used to treat hepatic coma and also to improve the intellectual development of children. In the food industry, MSG is a commonly used food flavor enhancer, and its main component is sodium glutamate. In the past, the production of MSG was mainly carried out by hydrolysis of wheat gluten (gluten), but now microbial fermentation is used for large-scale production.
L-glutamic acid is mainly used in the production of MSG, spices, and as salt substitutes, nutritional supplements, and biochemical reagents. L-glutamic acid itself can be used as a drug, participating in the metabolism of proteins and sugars in the brain, and promoting the oxidation process. This product combines with ammonia in the body to form non-toxic glutamine, which reduces blood ammonia and relieves the symptoms of hepatic coma.
Food Industry
Glutamic acid is one of the basic amino acids for nitrogen metabolism in biological organisms and is of great significance in metabolism. L-Glutamic acid is the main component of protein, and glutamate is ubiquitous in nature. Glutamate is contained in many foods and in the human body. It is one of the structural amino acids of proteins or peptides, and it is also a free amino acid. L-type amino acids are more delicious.
Daily Necessities
Glutamic acid is the most abundant amino acid in the world and can be used for skin and hair as a nutritional drug. Used as a hair growth agent, it can be absorbed by the scalp to prevent hair loss and regenerate hair. It has nutritional functions for dermal papillae and hair mother cells, can expand blood vessels, enhance blood circulation, and has the effect of hair growth and hair loss prevention. Used on the skin, it is effective in treating wrinkles.
Pharmaceutical Industry
Glutamic acid can also be used in medicine, because glutamic acid is one of the amino acids that make up protein. Although it is not an essential amino acid for the human body, it can participate in the body's metabolism as a carbon and nitrogen nutrition and has high nutritional value. After glutamic acid is absorbed by the human body, it easily forms glutamine with blood ammonia, which can relieve the toxic effects of ammonia during metabolism. Therefore, it can prevent and treat hepatic coma and protect the liver. It is an auxiliary drug for patients with liver diseases. Brain tissue can only oxidize glutamic acid, but not other amino acids. Therefore, glutamine can be used as an energy substance in brain tissue to improve and maintain brain function. As a supplement for the nerve center and cerebral cortex, glutamate has certain effects on the treatment of concussions or nerve injuries, epilepsy, and mentally retarded children.
Company Introduction And Certificates Obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Glutamic acid powder etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
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