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CAS NO:
65914-17-2
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Basic Info
CAS Number
65914-17-2
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Product Description
Giant knotweed extract polydatin is the glycoside of resveratrol originally isolated from the Chinese herb Polygonum cuspidatum.
The polydatin has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell studies report thatpolydatin can inhibit ICAM-1 expression, elevate Ca2+, weak en white blood cell-endothelial cell adhesion, and activate KATP channels.
AI Product Description
*The following content is generated by AI and is for reference only.
Giant Knotweed Extract, derived primarily from the roots of *Fallopia japonica* (Japanese Knotweed), is a potent botanical ingredient renowned for its high concentration of resveratrol and other polyphenolic compounds. While often marketed as a natural alternative to synthetic antioxidants, it is crucial to note that "Giant Knotweed Extract" refers to a complex mixture rather than a single chemical entity; therefore, it does not possess a singular molecular formula or a unique CAS number applicable to the raw extract itself. The primary bioactive constituent, trans-resveratrol, has the molecular formula C14H12O3 and the specific CAS registry number 501-36-0. However, commercial extracts vary significantly in purity and composition depending on the extraction method used, typically ranging from standard 98% resveratrol isolates to broader polyphenol profiles.
This versatile ingredient is extensively utilized across the cosmetic, nutraceutical, and pharmaceutical industries due to its robust biological activities. In skincare formulations, Giant Knotweed Extract serves as a powerful antioxidant, neutralizing free radicals generated by UV exposure and pollution. It helps inhibit tyrosinase activity, thereby reducing melanin production to brighten skin tone and fade hyperpigmentation. Furthermore, its anti-inflammatory properties make it effective for soothing irritated skin and managing conditions like acne. Within the dietary supplement sector, the extract is valued for supporting cardiovascular health, promoting healthy aging, and enhancing metabolic function through its ability to mimic caloric restriction effects. Research suggests potential benefits in neuroprotection and blood sugar regulation. As a sustainable, plant-based solution, it appeals to consumers seeking clean-label products with scientifically backed efficacy. Manufacturers often highlight its stability compared to some synthetic alternatives, ensuring long shelf-life in various product matrices. Whether formulated into serums, capsules, or functional foods, Giant Knotweed Extract remains a cornerstone ingredient in modern wellness and beauty regimens, bridging traditional herbal knowledge with contemporary scientific validation to deliver comprehensive health and aesthetic benefits.
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