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CAS NO:
108321-42-2
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Basic Info
CAS Number
108321-42-2
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Packaging & Delivery
Packaging Specification
as request
Product Description
Description
Geneticin (G418) Sulfate is an aminoglycoside antibiotic that has originally been derived from Micromonospora rhodoranga NRRL 5326. This compound has been shown to cause a bypass of nonsense mutations during translation. Experiments have shown that geneticin sulfate inhibits the incorporation of amino acids into protein and can destroy fibroblasts. Mechanistic studies suggest that this agent affects the 80S ribosome and inhibits the elongation cycle. Further studies report that geneticin sulfate is highly active against amoebae, protozoa, tapeworm, and pinworm exposed murine cells.
Usage
• Potency: ≥700 μg/mg
Technical Information
| Appearance: | Powder |
| Physical State: | Solid |
| Solubility: | Soluble in water (50 mg/ml) and aqueous buffers. |
| Storage: | Store at 4° C |
| Boiling Point: | 1012.1 °C at 760 mmHg (Predicted) |
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