*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Fosfomycin Trometamol is a <strong>semisynthetic antibiotic</strong> derived from fosfomycin, widely utilized for treating urinary tract infections. Its core synthesis involves the reaction of (1R,2S)-epoxypropylphosphonic acid with trometamol to enhance water solubility. The molecular formula is C<sub>9</sub>H<sub>20</sub>NO<sub>7</sub>P, and its CAS number is 458-26-4.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Primary active ingredient in formulations for uncomplicated cystitis.</li>
<li><strong>Urology:</strong> Standard treatment for acute lower urinary tract infections caused by susceptible strains.</li>
<li><strong>Research & Development:</strong> Used as a reference standard in microbiological assays and stability studies.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with severe renal impairment without dose adjustment. Store in a cool, dry place below 25°C to prevent hydrolysis. Strict adherence to GMP guidelines is required during handling to ensure product purity and safety.</p>