*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Folinic Acid, also known as <strong>Leucovorin</strong>, is a reduced form of folic acid. Its core synthesis involves the oxidation of folinic acid precursors via enzymatic pathways or chemical reduction. The molecular formula is <strong>C20H22N6O7</strong> with CAS No. <strong>58-05-9</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology:</strong> Used as a rescue agent in high-dose methotrexate therapy.</li>
<li><strong>Hematology:</strong> Treats megaloblastic anemia caused by folate deficiency.</li>
<li><strong>Diagnostics:</strong> Enhances fluorouracil efficacy in colorectal cancer treatment protocols.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with pernicious anemia without B12 supplementation. Store in cool, dry conditions below 25°C protected from light to maintain stability and prevent degradation.</p>