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Veterinary API
CAS NO:
864731-61-3
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Basic Info
CAS Number
864731-61-3
Pharmacopoeia
In-house Standards
Grade
Veterinary Grade
Is Manufacturer
YES
Samples Provided
YES
Product Description
TP available
USVMF 006505
This veterinary medicinal product is a systemic insecticide and acaricide that provides:
- immediate and persistent flea (Ctenocephalides canis and C. felis) killing activity for 1 month,
- immediate and persistent tick (Dermacentor reticulatus, Ixodes hexagonus, I. ricinus and Rhipicephalus sanguineus) killing activity for 1 month.
AI Product Description
*The following content is generated by AI and is for reference only.
Fluralaner, identified by CAS number 864731-61-3 and molecular formula C25H29F3N4O2S, represents a significant advancement in the field of veterinary parasitology. As a member of the isoxazoline class of compounds, it functions as a potent inhibitor of gamma-aminobutyric acid (GABA)-gated chloride channels and glutamate-gated chloride channels in insects and arachnids. This unique mechanism of action disrupts the nervous system of target parasites, leading to rapid paralysis and death.
Primarily utilized for the treatment and prevention of ectoparasitic infestations in dogs and cats, Fluralaner has revolutionized pet care with its extended duration of efficacy. Unlike traditional flea and tick products that require monthly application, Fluralaner offers protection for up to twelve weeks against fleas and ticks following a single oral or topical dose. It demonstrates exceptional speed of kill, often eliminating fleas within four hours and ticks within twelve hours of administration. The product is highly effective against major species such as *Ctenocephalides felis* (cat flea), *Ixodes scapularis* (black-legged tick), and *Rhipicephalus sanguineus* (brown dog tick). Furthermore, it provides robust control against sarcoptic mange caused by *Sarcoptes scabiei*.
The pharmacokinetic profile of Fluralaner allows for sustained release from the skin and subcutaneous tissues, ensuring continuous therapeutic levels in the bloodstream. Its safety margin is well-established for use in healthy adult animals, though caution is advised for puppies under specific weight thresholds or those with a history of seizures. Available in various formulations including chewable tablets and spot-on solutions, Fluralaner has become a cornerstone in modern integrated pest management strategies for companion animals. By significantly reducing the frequency of dosing required, it enhances owner compliance and improves the overall quality of life for pets while minimizing environmental exposure to frequent chemical applications.
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