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Basic Info
CAS Number
N/A
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Fluorometholone is a potent synthetic corticosteroid widely utilized in ophthalmology and dermatology for its anti-inflammatory, antipruritic, and immunosuppressive properties. With the chemical formula C23H29FO5 and a CAS registry number of 68-04-6, this compound belongs to the fluorinated glucocorticoid class. The presence of a fluorine atom at the C9 position significantly enhances its topical potency compared to non-fluorinated analogs like prednisolone, while maintaining a favorable safety profile for ocular tissues when used appropriately.
In clinical practice, Fluorometholone is primarily formulated as eye drops or ointments to treat various inflammatory conditions of the anterior segment of the eye. It is highly effective in managing allergic conjunctivitis, seasonal allergies, uveitis, and post-operative inflammation following cataract surgery or laser procedures. Unlike some stronger steroids such as dexamethasone, Fluorometholone exhibits lower aqueous humor penetration, which reduces the risk of elevating intraocular pressure—a critical advantage for patients with glaucoma or those prone to steroid-induced ocular hypertension. However, it is not without risks; prolonged use can still lead to increased eye pressure, cataract formation, or secondary infections if pre-existing viral or fungal eye diseases are present. Consequently, medical supervision is essential during treatment courses.
Beyond ophthalmology, the compound finds application in dermatological formulations for treating eczema, psoriasis, and contact dermatitis, although its primary market dominance remains in eye care. The drug works by inhibiting the synthesis of inflammatory mediators, including prostaglandins and leukotrienes, thereby reducing redness, swelling, and itching. Its molecular structure allows for high lipid solubility, facilitating penetration through corneal barriers. While generally well-tolerated, patients must be monitored for signs of infection, as the suppression of local immune responses may mask early symptoms of bacterial, fungal, or viral keratitis. Overall, Fluorometholone represents a balanced therapeutic option where moderate-to-high efficacy is required alongside minimized systemic and ocular side effects, making it a staple in modern anti-inflammatory regimens for sensitive tissues.
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