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Other Specialized Reagents

Factory Supply Atorvastatin calcium CAS 134523-03-8

Category:

Other Specialized Reagents

CAS NO:

134523-03-8

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Jianfeng Chemical Co., Ltd.

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Basic Info

CAS Number

134523-03-8

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Aliase: Atorvastatin calcium
Purity: 99%
Appearance:White powder
high quality: low price
Usage: A slecive, compettive HMG-COAreductase inibior Alovastatin is the only drug in ts class specall ndicated for lowerng both elevated LDLcholestrol and tiglycerides in patients with hyercolestrolemia.

AI Product Description

*The following content is generated by AI and is for reference only.

Atorvastatin Calcium, identified by the Chemical Abstracts Service (CAS) registry number 134523-03-8, is a widely utilized pharmaceutical intermediate and active ingredient in the global healthcare sector. Manufactured through rigorous factory supply chains to ensure high purity and consistency, this compound serves as the calcium salt of atorvastatin, a potent HMG-CoA reductase inhibitor. Its molecular formula is C66H68CaF2N4O10, reflecting its complex structure which includes two fluorophenyl rings and a pyrrole moiety essential for its biological activity. The primary therapeutic application of Atorvastatin Calcium lies in the management of dyslipidemia and the prevention of cardiovascular diseases. As a cornerstone treatment for lowering elevated cholesterol levels, it effectively reduces total cholesterol, low-density lipoprotein (LDL), apolipoprotein B, and triglycerides while simultaneously increasing high-density lipoprotein (HDL). By inhibiting the enzyme HMG-CoA reductase, the rate-limiting step in hepatic cholesterol synthesis, the drug decreases intracellular cholesterol pools, thereby upregulating LDL receptors on hepatocyte surfaces and enhancing the clearance of circulating LDL particles. Beyond lipid regulation, clinical evidence supports its role in stabilizing atherosclerotic plaques and reducing inflammation, significantly lowering the risk of myocardial infarction, stroke, and other major adverse cardiac events in patients with or without pre-existing heart disease. The calcium salt form offers improved stability and solubility compared to the free acid, facilitating better bioavailability and patient compliance in tablet formulations. In the industrial context, suppliers provide this substance under strict quality control standards, adhering to Good Manufacturing Practices (GMP) for use in large-scale drug production. It is a critical raw material for generic and brand-name statin manufacturers worldwide. Whether for research purposes or commercial pharmaceutical formulation, Factory Supply Atorvastatin Calcium remains an indispensable asset in modern medicine, offering a reliable solution for managing hypercholesterolemia and mitigating cardiovascular risks across diverse patient populations globally.