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Basic Info
CAS Number
N/A
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) belonging to the pyranocarboxylic acid class, widely recognized for its efficacy in managing pain and inflammation associated with various musculoskeletal disorders. Chemically, it possesses the molecular formula C18H23NO3 and carries the unique CAS registry number 60549-85-7. Its structural composition features a fused ring system that distinguishes it from other NSAIDs, contributing to its specific pharmacological profile. The primary mechanism of action involves the selective inhibition of cyclooxygenase enzymes, particularly COX-2, which are responsible for the synthesis of prostaglandins. By reducing prostaglandin levels at sites of inflammation, Etodolac effectively alleviates pain, reduces swelling, and improves joint mobility without causing significant gastric irritation compared to some traditional non-selective NSAIDs, although caution remains necessary.
Clinically, Etodolac is predominantly prescribed for the treatment of osteoarthritis and rheumatoid arthritis, offering patients relief from chronic joint pain and stiffness. It is also utilized in the management of acute pain conditions, such as post-operative discomfort or dental pain, due to its rapid onset of action and sustained therapeutic effect. Available in various formulations including immediate-release tablets, extended-release capsules, and topical gels, the drug allows for flexible dosing strategies tailored to individual patient needs. Typical dosages range from 200 mg to 600 mg daily, depending on the severity of symptoms and the specific formulation used. While generally well-tolerated, potential side effects may include gastrointestinal upset, dizziness, headache, and rare but serious cardiovascular risks associated with long-term NSAID use. Patients with a history of peptic ulcers, kidney disease, or heart failure require careful monitoring during therapy. As with all NSAIDs, Etodolac should be taken with food to minimize gastric distress. Ongoing research continues to explore its role in broader pain management protocols, solidifying its position as a valuable therapeutic agent in modern medicine for inflammatory conditions.
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