Product Description
Reference Standards &Impurity
AI Product Description
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Ergocalciferol, commonly known as Vitamin D2, is a vital fat-soluble vitamin essential for maintaining human health. Its chemical formula is C28H44O, and it carries the CAS Registry Number 50-14-6. Structurally, it is an analog of cholecalciferol (Vitamin D3) but derived from plant sources, specifically produced by the ultraviolet irradiation of ergosterol found in yeast or fungi. This unique biosynthetic pathway makes Ergocalciferol a preferred choice for vegetarians and vegans who avoid animal-derived supplements like those containing D3.
The primary function of Ergocalciferol revolves around calcium and phosphorus homeostasis within the body. Once ingested, it undergoes metabolic conversion in the liver and kidneys to become its active form, calcitriol. This active hormone regulates intestinal absorption of minerals, ensuring strong bone formation and preventing conditions such as rickets in children and osteomalacia in adults. Furthermore, emerging research suggests potential roles in immune system modulation and cardiovascular health, though these areas require further clinical validation.
In the pharmaceutical industry, Ergocalciferol is widely utilized in dietary supplements, prescription medications, and fortified foods like milk and cereals. It is particularly crucial for populations with limited sun exposure, darker skin tones, or specific dietary restrictions that hinder natural Vitamin D synthesis. Medical professionals often prescribe high-dose Ergocalciferol to treat severe deficiencies, hypoparathyroidism, or renal osteodystrophy. While generally safe when taken within recommended limits, excessive intake can lead to hypercalcemia, highlighting the importance of proper dosage monitoring. As a cost-effective and accessible source of Vitamin D, Ergocalciferol remains a cornerstone in global public health strategies aimed at combating widespread deficiency and promoting skeletal integrity worldwide.