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CAS NO:
141342-70-3
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ChP,
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Basic Info
CAS Number
141342-70-3
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Epinastine is a second-generation antihistamine belonging to the class of selective H1-receptor antagonists, widely utilized in the management of allergic conditions. Its chemical identity is defined by the molecular formula C24H28N2O and carries the CAS Registry Number 95079-39-9. Structurally, it features a complex tricyclic framework that distinguishes it from earlier generation agents, contributing to its high specificity for peripheral histamine receptors while minimizing central nervous system penetration. This pharmacological profile significantly reduces the incidence of sedation, a common side effect associated with first-generation antihistamines, thereby allowing patients to maintain normal cognitive function and daily activities without impairment.
The primary clinical application of Epinastine is the treatment of allergic rhinitis and allergic conjunctivitis. In the form of oral tablets or topical ophthalmic solutions, it effectively alleviates symptoms such as sneezing, nasal congestion, rhinorrhea, ocular itching, redness, and tearing. By blocking the binding of histamine to H1 receptors on smooth muscle cells and vascular endothelium, Epinastine inhibits the vasodilation and increased vascular permeability that characterize allergic inflammatory responses. Furthermore, emerging research suggests that Epinastine may possess additional anti-inflammatory properties, potentially stabilizing mast cells and reducing the release of other pro-inflammatory mediators beyond histamine.
Due to its favorable safety profile and rapid onset of action, Epinastine is frequently prescribed for both seasonal and perennial allergies. It is particularly valued in pediatric populations where non-sedating options are critical for school performance. While generally well-tolerated, mild adverse effects such as dry mouth, drowsiness (rare), or headache may occur. Patients are advised to follow dosage instructions strictly, typically involving once-daily oral administration or specific eye drop regimens depending on the formulation. As a versatile therapeutic agent, Epinastine represents a significant advancement in allergy management, offering effective symptom control with minimal disruption to quality of life, making it a cornerstone medication in modern allergology practice globally.
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