Category:
Reagents for Biopharmaceuticals
CAS NO:
989-51-5
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ChP,USP,EP,
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Basic Info
CAS Number
989-51-5
Pharmacopoeia
ChP,USP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
As your requirements
Minimum Order Quantity
1 kg
Delivery Cycle
2-5days
Product Description
Common Name： Epigallocatechin gallate
Molecular Formula： C11H12N2O3
Molecular Weight： 220.225
CAS： 989-51-5
Epigallocatechin Gallate (EGCG) inhibits activation EGFR, HER2 and HER3 in the SW837 human colon cancer cell line. (-)-Epigallocatechin Gallate (10 μM) also inhibits cell growth, suppresses activation of EGFR, HER2, and HER3, and causes decrease in the levels of COX-2 and Bcl-xL proteins, and apoptosis after treatment for 96 h[1]. (-)-Epigallocatechin Gallate (0-35 μg/mL) inhibits the proliferation of colorectal cancer cells. (-)-Epigallocatechin Gallate (35 μg/mL) induces apoptosis of colorectal cancer cells[2]. (-)-Epigallocatechin Gallate (EGCG; 50, 75 and 100 μM) dose-dependently inhibits the growth of HepG2 cells, and induces apoptosis in HepG2 cells[3].
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