The DS-BIOAT automatic reciprocating cylinder dissolution system consists of a reciprocating cylinder dissolution device and an automatic sampling workstation. Meet the relevant requirements of the US Pharmacopoeia, Chinese Pharmacopoeia and European Pharmacopoeia. The device adopts a transparent hollow cylinder equipped with screens at both ends. The sample to be tested is placed in the cylinder and the screens at both ends are tightened before being placed in a dissolution cup containing dissolution medium and gently reciprocating up and down. The dissolution medium flows through a reciprocating cylinder through a sieve, providing shear force at the liquid-solid interface during the dissolution process of the drug. Suitable for the dissolution study of new drug formulations such as sustained-release, targeted release, and enteric coated delayed release formulations.