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CAS NO:
520-27-4
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Basic Info
CAS Number
520-27-4
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Diosmin is a naturally occurring flavonoid glycoside derived primarily from hesperidin, a compound found in the peels of citrus fruits. Chemically classified as a benzopyrone derivative, its molecular formula is C28H32O15, and it is uniquely identified by the CAS number 520-27-4. This bioactive substance serves as a cornerstone in the pharmaceutical industry, particularly for the management of chronic venous insufficiency (CVI) and hemorrhoidal disorders.
The primary mechanism of action for Diosmin involves enhancing venous tone and reducing capillary permeability. By strengthening the structural integrity of blood vessel walls, it effectively mitigates symptoms such as leg heaviness, pain, swelling, and cramping associated with poor circulation. Furthermore, Diosmin exhibits potent anti-inflammatory and antioxidant properties, which help reduce oxidative stress and improve microcirculation in affected tissues. These combined effects make it a highly effective treatment for acute hemorrhoidal attacks, where it aids in reducing bleeding, edema, and inflammation.
Clinically, Diosmin is often administered orally in micronized or phytosome formulations to enhance bioavailability and absorption rates. It is widely recognized for its favorable safety profile, with minimal side effects reported even during long-term use. While frequently used as a standalone therapy, it is also commonly prescribed in combination with other bioflavonoids like hesperidin to maximize therapeutic outcomes. Beyond human medicine, research continues to explore its potential applications in treating lymphatic disorders and improving wound healing processes due to its regenerative capabilities on vascular endothelium.
In summary, Diosmin stands out as a vital natural remedy for venous and lymphatic health issues. Its ability to restore normal vascular function while providing anti-inflammatory relief has secured its position as a standard treatment option globally. As demand for natural, plant-based therapeutics grows, Diosmin remains a key ingredient in developing advanced cardiovascular and venous care products, offering patients significant relief from debilitating circulatory conditions without the harsh side effects often associated with synthetic alternatives.
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