1.Product name:Diclofenac Gel 2.Specification: 1.16%,30g; 1.16%,50g;5g:0.3% 3.Package:1 bottle/box 4.Shelf life:36 months 5.Registration docoments are available. If you are interested in our products,ple feel free to contact us.
*The following content is generated by AI and is for reference only.
Diclofenac Gel is a widely utilized topical nonsteroidal anti-inflammatory drug (NSAID) designed for the local treatment of pain and inflammation associated with various musculoskeletal conditions. Chemically known as Diclofenac Sodium or Diclofenac Diethylamine depending on the specific salt formulation, its molecular formula is C14H10Cl2NNaO2 for the sodium salt variant. The compound is identified by the CAS Registry Number 15307-86-5. This medication functions primarily by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are lipid compounds that mediate inflammation, pain, and fever at the site of injury. By reducing their production locally within the tissues, Diclofenac Gel effectively alleviates discomfort without causing the systemic side effects often associated with oral NSAIDs, such as gastrointestinal distress or increased cardiovascular risk.
The primary indications for this gel include the management of acute soft tissue injuries like sprains, strains, and contusions, as well as chronic conditions such as osteoarthritis in superficial joints like the knees and hands. It is also frequently prescribed for localized muscle pain, tendonitis, and bursitis. The gel formulation offers significant advantages regarding bioavailability; it allows the active ingredient to penetrate the skin directly to the affected area, achieving high local concentrations while maintaining low systemic absorption. This targeted delivery mechanism makes it particularly suitable for patients who cannot tolerate oral medications or require rapid relief from localized symptoms. Application typically involves massaging a small amount of the gel gently onto the clean, dry skin over the painful area two to four times daily, depending on the specific product instructions and severity of symptoms. While generally safe, users should avoid applying the gel to broken skin or mucous membranes and discontinue use if signs of allergic reaction or severe skin irritation occur. Overall, Diclofenac Gel remains a cornerstone therapy in pain management due to its efficacy, safety profile, and ease of application.