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CAS NO:
2392-39-4
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ChP,
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Basic Info
CAS Number
2392-39-4
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Dexamethasone Sodium Phosphate is a potent, water-soluble corticosteroid derivative widely utilized in clinical medicine for its rapid onset of action and anti-inflammatory properties. Chemically known as dexamethasone 21-phosphate sodium salt, this compound features the molecular formula C22H28NaFO8P and carries the CAS Registry Number 2392-39-4. It serves as a prodrug that is rapidly converted into active dexamethasone within the body, allowing for efficient systemic distribution when administered via intravenous or intramuscular routes. The primary therapeutic application of Dexamethasone Sodium Phosphate lies in the management of severe inflammatory conditions, including rheumatoid arthritis, acute asthma exacerbations, and allergic reactions such as anaphylaxis. Beyond inflammation, it is frequently employed to reduce cerebral edema associated with brain tumors, treat adrenal insufficiency during stress, and manage certain hematologic malignancies like leukemia and lymphoma. Its high solubility makes it particularly advantageous for emergency settings where immediate pharmacological effect is critical. Furthermore, it plays a significant role in preventing nausea and vomiting induced by chemotherapy regimens. While highly effective, long-term use requires careful monitoring due to potential side effects such as immunosuppression, hyperglycemia, osteoporosis, and fluid retention. As a synthetic glucocorticoid, it possesses a much higher anti-inflammatory potency compared to hydrocortisone but exhibits minimal mineralocorticoid activity, reducing the risk of sodium retention. In pharmaceutical formulations, it is available as sterile solutions for injection, ensuring precise dosing in hospital environments. This versatile agent remains a cornerstone in modern therapeutics, bridging the gap between acute symptom relief and chronic disease management across various medical specialties.
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