Dasatinib, also known as DASA tin IB, is a pale to yellow solid chemical. Chemical name N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl) piperazine-1-group] -2-methyrimidine-4-group] amino]-1, 3-thiazole-5-formamide, molecular formula is C22H26ClN7O2S, molecular weight is 488.00600. Dasatinib is an anti-tumor drug, which is mainly used to treat adult patients with Philadelphia chromosomal positive (Ph+) chronic myeloid leukemia (CML) that are resistant to imatinib mesylate or are not tolerant to it.
Molecular weight: 488.00600
Accurate quality: 487.15600
PSA: 134.75000
LogP: 3.46240 [1]
Physical and chemical properties
Appearance and appearance: gray-yellow solid
Density: 1.408 g/cm3
Melting point: 275-286 ° C