Chromatographic packing is the core of drug separation and purification, and contemporary drug scientists and synthesizers are given the requirement of faster, higher and purer in their experiments. According to the physical and chemical properties and functional groups of the separated drugs or compounds, different bonding phases are selected, such as reversed-phase chromatography (C18, C8, C4), normal-phase chromatography (Sil, Diol, CN, Pheny), polymer packing (PS/DVB or PMMA), according to the size of the molecular weight and the structure of the molecule to choose a different size of the Division (100A, 200A, 300A, 1000A), according to the difficulty of separation to choose the pull size (5um), the size of the pull size (5um), according to the separation difficulty to choose the pull size (5um). According to the difficulty of separation, we choose the size of pulling diameter such as (5um, 10um, 15um, 20um, 30um).