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CAS NO:
22818-40-2
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Basic Info
CAS Number
22818-40-2
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Cefprozil is a second-generation cephalosporin antibiotic widely utilized in clinical settings for the treatment of various bacterial infections. Chemically known as (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-hydroxyethoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, it possesses a distinct molecular structure that enhances its stability against certain beta-lactamases compared to earlier generations. The specific molecular formula is C16H17N3O6S, and its unique identifier, the CAS registry number, is 94283-23-5. This compound typically exists as a white to off-white crystalline powder, often formulated as cefprozil monohydrate for oral administration in tablet or suspension forms.
The primary therapeutic application of Cefprozil targets respiratory tract infections, including acute otitis media, pharyngitis, tonsillitis, and community-acquired pneumonia caused by susceptible strains of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Additionally, it is effective against uncomplicated skin and soft tissue infections induced by Staphylococcus aureus and Streptococcus pyogenes. Its mechanism of action involves the inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins, thereby preventing the cross-linking of peptidoglycan layers essential for bacterial structural integrity. This bactericidal activity leads to rapid cell lysis and death.
One significant advantage of Cefprozil is its pharmacokinetic profile, which allows for twice-daily dosing due to its extended half-life and good bioavailability. It exhibits excellent tissue penetration, particularly in the middle ear fluid and respiratory secretions, making it highly suitable for pediatric and adult patients suffering from recurrent infections. While generally well-tolerated, common side effects may include gastrointestinal disturbances such as diarrhea, nausea, and abdominal pain. Allergic reactions, ranging from mild rashes to severe anaphylaxis, remain a critical consideration, especially for patients with a history of hypersensitivity to penicillins or other cephalosporins. As with all antibiotics, prudent prescribing practices are essential to mitigate the growing threat of antimicrobial resistance. Cefprozil remains a valuable tool in modern medicine for managing common bacterial pathogens efficiently and safely.
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