Yellowish to yellow crystalline or amorphous powders, no smell. The product dissolves in water and can not dissolve in ethanol or ether, and it easily dissolves in 0.1mol/L sodium hydroxide solution.
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Calcium Folinate</strong> is a calcium salt of leucovorin, serving as a reduced folate cofactor. It is synthesized via enzymatic reduction of folic acid followed by calcium salt formation. CAS No: 58-05-9.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology:</strong> Rescue therapy for methotrexate toxicity and combination with fluorouracil in colorectal cancer.</li>
<li><strong>Hematology:</strong> Treatment of megaloblastic anemia caused by folate deficiency.</li>
<li><strong>Research:</strong> Nutritional supplement in cell culture media for metabolic studies.</li>
</ul>
<h3>Precautions</h3>
<p>Avoid use in cyanocobalamin (B12) deficiency to prevent masking neurological symptoms. Store in cool, dry conditions below 25°C away from light. Strict adherence to clinical dosing protocols is required to avoid adverse interactions.</p>