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CAS NO:
20123-80-2
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Basic Info
CAS Number
20123-80-2
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Calcium Dobesilate, chemically known as calcium 2,5-dihydroxybenzenesulfonate, is a widely utilized pharmaceutical agent primarily employed in the management of chronic venous insufficiency and various microcirculatory disorders. With the molecular formula C12H10CaO7S2 and a CAS registry number of 3689-43-6, this compound represents the calcium salt of dobesilic acid. Its distinctive chemical structure facilitates potent pharmacological activity aimed at improving vascular integrity and reducing capillary permeability.
The primary clinical application of Calcium Dobesilate centers on alleviating symptoms associated with venous hypertension, such as leg heaviness, pain, cramps, and edema. It is particularly effective in treating conditions like hemorrhoids, diabetic retinopathy, and varicose veins. The drug functions by strengthening capillary walls, thereby preventing plasma leakage into surrounding tissues. Furthermore, it exhibits anti-inflammatory properties that help reduce local swelling and discomfort. By enhancing blood flow and reducing blood viscosity, it supports overall microcirculation, making it a valuable therapeutic option for patients suffering from compromised venous return.
Beyond its direct vascular effects, Calcium Dobesilate is often prescribed to manage complications arising from diabetes, specifically microangiopathy affecting the eyes and kidneys. Its ability to protect endothelial cells makes it a critical component in long-term treatment strategies for maintaining tissue health in diabetic patients. The medication is generally administered orally in tablet or capsule form, offering a convenient dosage regimen for chronic management. While side effects are typically mild and may include gastrointestinal disturbances or skin rashes, the drug is considered safe for most adults when used according to medical guidelines. Extensive clinical studies have confirmed its efficacy across diverse populations, solidifying its status as a standard therapy for venous and microvascular pathologies worldwide. As a result, Calcium Dobesilate remains a cornerstone in the pharmacological arsenal for treating circulatory disorders, providing significant relief and improved quality of life for millions of patients globally.
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