*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Busulfan</strong> is a potent alkylating agent used primarily in chemotherapy. Synthesized via methanesulfonic acid esterification, its molecular formula is <strong>C6H14O4S2</strong> (CAS No. 55-98-1).</p>
<h3>Application</h3>
<ul>
<li>Hematologic malignancies: Conditioning regimen for hematopoietic stem cell transplantation.</li>
<li>Chronic Myeloid Leukemia (CML): Management of myeloproliferative disorders.</li>
<li>Myeloablative therapy: Pre-transplant preparation to eliminate malignant cells.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated without medical supervision due to severe pulmonary toxicity and carcinogenicity. Store in tightly sealed containers at controlled room temperature away from moisture. Handle with full PPE to prevent inhalation or skin contact.</p>