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CAS NO:
611-75-6
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ChP,
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Basic Info
CAS Number
611-75-6
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Bromhexine is a widely utilized pharmaceutical agent belonging to the class of mucolytic drugs, primarily employed in the management of respiratory disorders characterized by excessive or viscous mucus production. Its chemical identity is defined by the molecular formula C14H23BrN2O, and it is universally recognized by its CAS Registry Number 158-96-7. Structurally, Bromhexine acts as a synthetic derivative of vasicine, an alkaloid originally isolated from the Indian plant *Adhatoda vasica*. The drug functions through a dual mechanism: it disrupts the structural integrity of acidic mucopolysaccharide fibers within sputum, thereby reducing viscosity, and simultaneously stimulates the secretion of serous components from bronchial glands to facilitate easier clearance.
Clinically, Bromhexine is indicated for acute and chronic conditions such as bronchitis, asthma, emphysema, cystic fibrosis, and pneumonia where thick mucus impedes airway patency. By liquefying secretions, it enhances the efficiency of the ciliary escalator, allowing patients to expel phlegm more effectively without the need for forceful coughing, which can be damaging to lung tissue. It is available in various formulations including tablets, syrup, and injectable solutions, making it suitable for both pediatric and adult populations. While generally well-tolerated, minor side effects may include gastrointestinal disturbances or transient allergic reactions. Notably, Bromhexine is often used in combination with other expectorants or antibiotics to maximize therapeutic outcomes in complex respiratory infections. Its affordability and established safety profile have secured its position as a first-line therapy in many healthcare systems globally. As research continues, new delivery methods are being explored to improve bioavailability and target specific lung regions more precisely. Overall, Bromhexine remains a cornerstone in respiratory pharmacotherapy, offering significant relief to millions suffering from obstructive lung diseases by restoring normal mucociliary function and improving overall quality of life.
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