LEAPChem supplies high quality fine chemicals, intermediates and APIs.
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Bosutinib is a dual SRC/ABL tyrosine kinase inhibitor developed for <strong>chronic myeloid leukemia (CML)</strong>. It features a specific synthesis route targeting resistant mutations. <strong>Molecular Formula</strong>: C<sub>25</sub>H<sub>24</sub>N<sub>6</sub>O<sub>2</sub>; <strong>CAS No.</strong>: 859217-09-1.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology Manufacturing:</strong> Production of second-line therapies for TKI-resistant CML patients.</li>
<li><strong>Clinical Trials:</strong> Supply of active pharmaceutical ingredients for Phase III efficacy studies.</li>
<li><strong>Research & Development:</strong> Raw material for academic investigations into kinase inhibition mechanisms.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated in severe hepatic impairment without dose adjustment. Requires storage at controlled room temperature (20-25°C) with low humidity protection to maintain chemical stability.</p>