LEAPChem supplies high quality fine chemicals, intermediates and APIs.
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Bicine is a zwitterionic buffering agent widely utilized in biochemical research. Synthesized via the reaction of glycine with <strong>bis(2-hydroxyethyl)amine</strong>, it maintains stability across a broad pH range. Its chemical structure is defined by the molecular formula <strong>C6H13N2O4</strong> and CAS number <strong>5087-69-0</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Protein Purification:</strong> Serves as an effective buffer for ion-exchange chromatography to preserve protein conformation.</li>
<li><strong>Cell Culture:</strong> Used in media formulations to regulate pH without interfering with enzymatic assays.</li>
<li><strong>Electrophoresis:</strong> Functions as a key component in Tris-Bicine systems for high-resolution separation.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li>Not approved for direct human clinical administration; strictly for laboratory use only.</li>
<li>Store in a cool, dry environment away from moisture to prevent hygroscopic degradation.</li>
<li>Handle with appropriate PPE to avoid skin or eye irritation during bulk handling.</li>
</ul>