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5593-20-4
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Basic Info
CAS Number
5593-20-4
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Betamethasone dipropionate is a potent synthetic glucocorticoid belonging to the class of corticosteroids, widely utilized in dermatological medicine for its strong anti-inflammatory and immunosuppressive properties. With the Chemical Abstracts Service (CAS) registry number 3823-61-4, this compound features the molecular formula C25H31FO6. Its chemical structure includes two hydroxyl groups and a fluorine atom at the 9-alpha position, which significantly enhances its lipophilicity and topical potency compared to earlier generation steroids like hydrocortisone or betamethasone valerate. This structural modification allows for deeper penetration into the skin layers while minimizing systemic absorption when applied correctly, making it highly effective for localized treatment protocols.
The primary clinical application of Betamethasone dipropionate involves the management of various inflammatory and pruritic skin conditions. It is frequently prescribed for severe cases of psoriasis, atopic dermatitis, eczema, and lichen planus where milder steroid preparations have proven insufficient. The drug works by inhibiting the synthesis of pro-inflammatory mediators, reducing vasodilation, and suppressing the migration of leukocytes to the site of inflammation. Consequently, it effectively alleviates symptoms such as redness, swelling, itching, and scaling associated with these chronic skin disorders. In addition to dermatology, it is occasionally formulated in combination products for treating other cutaneous ailments, including discoid lupus erythematosus and seborrheic dermatitis.
Available typically as an ointment, cream, or lotion, the formulation depends on the severity of the condition and the specific body area being treated. Due to its high potency, it is generally classified as a Class I super-potent topical corticosteroid, requiring careful medical supervision to avoid adverse effects such as skin thinning, striae, telangiectasia, or hypothalamic-pituitary-adrenal axis suppression, particularly with prolonged use or application over large surface areas. Patients are advised to follow strict dosage guidelines provided by healthcare professionals. While not intended for systemic administration in this form, its pharmacological profile remains a cornerstone in modern dermatologic therapy, offering rapid relief for patients suffering from stubborn inflammatory skin diseases that resist less aggressive treatments.
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