*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Beta-D-homoDNA-T Phosphoramidite is a specialized modified nucleoside building block for solid-phase oligonucleotide synthesis. It features a homocytidine backbone modification enhancing nuclease resistance. <strong>Molecular Formula</strong>: C19H26N4O7P; <strong>CAS No.</strong>: 188560-36-5.</p>
<h3>Application</h3>
<ul>
<li><strong>Antisense Therapy</strong>: Synthesis of stable antisense oligonucleotides targeting specific mRNA sequences.</li>
<li><strong>Research Tools</strong>: Development of high-affinity probes for gene expression studies and diagnostics.</li>
<li><strong>Structural Biology</strong>: Creation of modified DNA duplexes to investigate backbone conformational effects.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis. Handle in a fume hood due to potential toxicity of phosphoramidites. Not intended for direct clinical use without rigorous purification and formulation validation.</p>