Category:
Reagents for Biopharmaceuticals
CAS NO:
633-66-9
Standard:
ChP,USP,EP,
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Basic Info
CAS Number
633-66-9
Pharmacopoeia
ChP,USP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
As your requirements
Minimum Order Quantity
10 gram
Delivery Cycle
6-10days
Product Description
Product Name：Berberine hydrogen sulphate
CAS Number ：633-66-9
Molecular Weight ：433.432
Molecular Formula： C20H19NO8S
Berberine sulfate is a natural alkaline, reduces apoptosis, with potent anti-oxidative and anti-inflammatory effect.
AI Product Description
*The following content is generated by AI and is for reference only.
Berberine hydrogen sulphate is a specialized chemical derivative of the well-known alkaloid berberine, designed to enhance solubility and bioavailability for various pharmaceutical and research applications. While native berberine exhibits limited water solubility due to its rigid molecular structure, the formation of the hydrogen sulfate salt significantly improves its dissolution properties in aqueous media. This modification allows for more efficient absorption in biological systems, making it a valuable alternative for therapeutic interventions targeting metabolic disorders.
The molecular formula for Berberine hydrogen sulphate is typically represented as C20H18NO4+·HSO4-, reflecting the protonated quaternary ammonium cation paired with the bisulfate anion. Its precise CAS number is 6395-78-6, which serves as a unique identifier for inventory management and regulatory compliance in scientific databases. Unlike the free base form, this salt form is often preferred in liquid formulations, injectables, or high-concentration solutions where standard berberine would precipitate.
In terms of utility, Berberine hydrogen sulphate retains the broad-spectrum pharmacological activities associated with its parent compound. It is extensively studied for its ability to activate AMP-activated protein kinase (AMPK), thereby regulating glucose metabolism, improving insulin sensitivity, and lowering lipid profiles. Consequently, it plays a critical role in managing type 2 diabetes, obesity, and cardiovascular diseases. Beyond human medicine, it finds application in veterinary science for treating infections and digestive issues in livestock. Additionally, researchers utilize this compound in biochemical assays to investigate antimicrobial mechanisms against resistant bacterial strains and fungal pathogens. The enhanced stability and solubility also facilitate its use in cosmetic formulations aimed at anti-inflammatory skin treatments. As global demand for natural metabolites grows, this salt form represents a crucial advancement in delivering the potent benefits of berberine through modern delivery systems, ensuring consistent efficacy across diverse clinical and industrial settings while maintaining safety profiles established by decades of traditional usage.
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