1.Product Name:Benzathine Penicillin Sodium For Injection
2.Specification:2.4Mega
3.Packing:50vials/box
4.Shelf Life:36 months
5.Registration documents are available.
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*The following content is generated by AI and is for reference only.
Benzathine Penicillin Sodium for Injection is a long-acting antibiotic formulation primarily utilized to treat infections caused by susceptible streptococcal organisms. Unlike other penicillin variants, this preparation releases the active drug slowly into the bloodstream over an extended period, typically maintaining therapeutic levels for up to four weeks following a single intramuscular dose. Its most prominent clinical application is the treatment of early syphilis and the prevention of rheumatic fever recurrence in patients with a history of rheumatic heart disease. Additionally, it serves as a crucial prophylactic agent against group A beta-hemolytic streptococcus in individuals who cannot tolerate oral antibiotics or require strict adherence to therapy.
The medication is administered exclusively via deep intramuscular injection, usually into the upper outer quadrant of the gluteal muscle, due to its viscous nature which precludes intravenous use. It is strictly contraindicated in patients with a known hypersensitivity to penicillins or cephalosporins, as administration can trigger severe, potentially fatal anaphylactic reactions. Healthcare providers must observe patients closely immediately after injection and have emergency resuscitation equipment readily available. Common side effects include pain at the injection site, local induration, and mild gastrointestinal disturbances.
Special caution is required when treating pregnant women, although penicillin remains the preferred treatment for syphilis during pregnancy to prevent congenital transmission. Patients with renal impairment may require dosage adjustments, though the drug is generally safe for most populations. Cross-sensitivity with other beta-lactam antibiotics should be considered. Before initiating therapy, a thorough patient history regarding allergies must be obtained. This product is not indicated for acute meningitis or rapid-onset infections requiring immediate high serum concentrations. Proper storage at controlled room temperature away from light ensures stability. Adherence to the prescribed dosing schedule is vital for preventing antibiotic resistance and ensuring complete eradication of the pathogen. Always consult current medical guidelines and package inserts for specific regional indications and updated safety profiles before clinical use.