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CAS NO:
4419-39-0
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ChP,
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Basic Info
CAS Number
4419-39-0
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Beclomethasone is a potent synthetic glucocorticoid widely utilized in the management of inflammatory and allergic conditions, particularly within the respiratory system. Its chemical identity is defined by the molecular formula C22H29ClO6, with a corresponding CAS Registry Number of 5534-08-7. Structurally, it belongs to the class of corticosteroids characterized by a steroid nucleus modified with chlorine and hydroxyl groups, which significantly enhances its anti-inflammatory potency while minimizing systemic absorption when administered via inhalation.
The primary clinical application of beclomethasone involves the long-term control of asthma. It acts as a maintenance therapy rather than a rescue medication, helping to reduce airway inflammation, mucus production, and bronchial hyperresponsiveness. By inhibiting the release of inflammatory mediators such as prostaglandins and leukotrienes, it effectively prevents asthma exacerbations and improves lung function over time. Beyond asthma, beclomethasone is frequently prescribed for the treatment of chronic rhinitis, including both seasonal and perennial allergic rhinitis, where it alleviates symptoms like nasal congestion, sneezing, and itching. It may also be employed in the management of certain dermatological disorders and inflammatory bowel diseases, though these uses are less common compared to its respiratory indications.
Available in various formulations, including metered-dose inhalers (MDIs), dry powder inhalers (DPIs), and nasal sprays, beclomethasone is designed to deliver high local concentrations directly to the target tissue. This targeted delivery system minimizes systemic side effects, making it a preferred choice for pediatric and adult patients requiring chronic therapy. Despite its safety profile, users must adhere strictly to prescribed dosages to avoid potential adverse effects such as oral thrush or hoarseness, which can often be mitigated by rinsing the mouth after inhalation. As a cornerstone in modern respiratory pharmacotherapy, beclomethasone remains essential for achieving optimal disease control and enhancing the quality of life for millions of patients suffering from chronic inflammatory airway diseases globally.
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