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Preclinical Research Services
CAS NO:
70356-09-1
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ChP,
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Basic Info
CAS Number
70356-09-1
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Avobenzone, chemically known as butyl methoxydibenzoylmethane, is a widely utilized organic compound primarily serving as a critical active ingredient in modern sunscreen formulations. With the molecular formula C20H22O3 and a CAS registry number of 70356-09-1, this substance stands out for its unique ability to absorb the full spectrum of UVA radiation, specifically within the 320 to 400 nanometer range. Unlike many other filters that focus on UVB protection, Avobenzone fills a vital gap by shielding skin from aging rays that penetrate deep into the dermis, thereby preventing photoaging, collagen degradation, and long-term DNA damage associated with premature wrinkling and loss of elasticity.
In commercial applications, Avobenzone is almost exclusively found in topical sunscreens, moisturizers, lip balms, and cosmetic foundations designed for daily photoprotection. Its high absorption efficiency allows manufacturers to formulate products with lower concentrations while maintaining effective broad-spectrum coverage. However, its chemical structure presents stability challenges; Avobenzone is notoriously prone to photodegradation when exposed to sunlight, losing potency over time if not properly stabilized. To counteract this, formulators frequently combine it with stabilizing agents such as octocrylene, homosalate, or specific antioxidants like tocopherol, which help maintain its efficacy throughout product shelf life and application duration.
Despite these formulation complexities, Avobenzone remains a gold standard in dermatological skincare due to its unmatched UVA coverage capabilities. It is approved for use in various global markets, including the United States, the European Union, and Asia, subject to concentration limits typically ranging from 2% to 3%. While some consumers express concerns regarding potential skin irritation or endocrine disruption, extensive regulatory reviews by agencies like the FDA and SCCS have deemed it safe for use within established guidelines. As the demand for comprehensive sun protection grows, Avobenzone continues to be an indispensable component in protecting human skin against the harmful effects of solar radiation, ensuring both immediate defense and long-term skin health preservation.
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