Category:
Cardiovascular System Drugs
CAS NO:
134523-03-8
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Basic Info
CAS Number
134523-03-8
Pharmacopoeia
ChP
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
NO
Product Description
As the therapy the Cardiovascular
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AI Product Description
*The following content is generated by AI and is for reference only.
Atorvastatin Calcium, commonly known by its brand name Lipitor, is a widely prescribed pharmaceutical agent belonging to the statin class of drugs. Chemically, it functions as an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, a key enzyme in the cholesterol biosynthesis pathway within the liver. The molecular formula for Atorvastatin Calcium is C66H68CaF2N4O10S2, reflecting its complex structure which includes calcium as a counterion to enhance stability and solubility. Its unique Chemical Abstracts Service (CAS) registry number is 134521-79-6, serving as a definitive identifier for this specific compound in global regulatory and scientific databases.
The primary clinical application of Atorvastatin Calcium is the management of dyslipidemia and the reduction of cardiovascular risk. It is highly effective in lowering low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol, while simultaneously raising high-density lipoprotein (HDL) levels and reducing triglycerides. By modulating lipid profiles, this medication plays a critical role in preventing atherosclerosis, thereby significantly decreasing the likelihood of myocardial infarction, stroke, and other major cardiovascular events in patients with or without pre-existing heart disease. Furthermore, it is frequently utilized in individuals with type 2 diabetes who are at elevated risk for cardiac complications due to their metabolic condition.
Beyond lipid management, Atorvastatin Calcium exhibits pleiotropic effects, including anti-inflammatory properties and improvement of endothelial function, which contribute to its overall therapeutic efficacy. The drug is administered orally, typically once daily, and demonstrates a long half-life that allows for flexible dosing schedules regardless of meal times. As one of the most extensively studied and prescribed medications worldwide, it has set a benchmark in preventive cardiology. Its widespread use underscores its importance in modern medicine for mitigating the burden of chronic cardiovascular diseases, making it an essential component of comprehensive treatment strategies aimed at improving patient longevity and quality of life through proactive risk factor modification.
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