Product Description
Reference Standards &Impurity
AI Product Description
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Arbidol, chemically known as Umifenovir, is a broad-spectrum antiviral agent widely utilized in the treatment and prophylaxis of influenza A and B infections. Its molecular formula is C22H25BrN2O3S, with a precise CAS registry number of 126408-93-7. Structurally, Arbidol features an indole core substituted with a bromine atom and a dimethylamino group, which plays a critical role in its mechanism of action. The drug functions primarily by inhibiting viral fusion with host cell membranes, thereby preventing the entry of the virus into cells. Additionally, it enhances the immune response by stimulating interferon production and increasing non-specific resistance to viral pathogens.
Originally developed in Russia, Arbidol has gained significant regulatory approval in China, Russia, and several other countries for managing seasonal and pandemic influenza. It is particularly valued for its efficacy when administered early in the infection course, reducing symptom severity and shortening the duration of illness. Beyond influenza, research suggests potential activity against other enveloped viruses, including coronaviruses, though further clinical validation is ongoing. The medication is available in various formulations, including tablets, capsules, and powders for suspension, catering to different age groups and patient needs. Safety profiles indicate that Arbidol is generally well-tolerated, with mild side effects such as allergic reactions or gastrointestinal discomfort being rare. Its oral bioavailability allows for convenient administration without the need for intravenous delivery. As global health challenges evolve, Arbidol remains a key component in antiviral strategies, especially in regions where rapid access to effective treatments is crucial. While not universally approved in Western markets like the United States or Europe, its widespread use in Asia and Eastern Europe underscores its importance in public health initiatives. Continued studies aim to expand its therapeutic applications and optimize dosing protocols for diverse viral strains.