Yellowish to yellow crystalline or amorphous powders
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Amrinone</strong> is a non-glycoside inotropic agent used for short-term management of heart failure. It functions as a phosphodiesterase-3 inhibitor to enhance myocardial contractility and reduce afterload. The molecular formula is C<sub>12</sub>H<sub>13</sub>N<sub>3</sub>O<sub>2</sub>, with CAS No. 829-74-5.</p>
<h3>Application</h3>
<ul>
<li><strong>Cardiology:</strong> Acute decompensated heart failure unresponsive to standard therapy.</li>
<li><strong>Perioperative Care:</strong> Hemodynamic support during cardiac surgery weaning from bypass.</li>
<li><strong>Research:</strong> Pharmacological studies on cAMP signaling pathways.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated in patients with severe thrombocytopenia or hypersensitivity. Must be stored in cool, dry conditions away from light. Monitor platelet counts regularly due to risk of hematologic toxicity.</p>