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<h3>Overview</h3>
<p>Amrinone (CAS: 821-54-9) is a <strong>bipyridine phosphodiesterase inhibitor</strong> used as an inotropic agent. Its molecular formula is <strong>C10H9N3O2</strong>. The compound is synthesized via condensation reactions involving 3,4-dimethyl-5-pyrazolone and chloroacetyl chloride.</p>
<h3>Application</h3>
<ul>
<li><strong>Cardiovascular Therapy:</strong> Short-term management of severe heart failure refractory to standard therapy.</li>
<li><strong>Hemodynamic Support:</strong> Improving cardiac output and reducing pulmonary capillary wedge pressure.</li>
<li><strong>Research Chemicals:</strong> Used in pharmacological studies regarding myocardial contractility mechanisms.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated for patients with idiopathic hypertrophic subaortic stenosis. Requires monitoring for thrombocytopenia and hepatic dysfunction. Store in a cool, dry place away from light to maintain stability.</p>