*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Amphotericin B is a polyene antifungal antibiotic produced by <strong>Saccharopolyspora nodosum</strong>. Its molecular formula is C<sub>47</sub>H<sub>73</sub>NO<sub>17</sub> and CAS number is 1397-89-3. The core manufacturing process involves fermentation followed by extraction and purification.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Treatment of severe systemic fungal infections like cryptococcal meningitis.</li>
<li><strong>Research:</strong> Used in laboratory studies for membrane permeability and ion channel research.</li>
<li><strong>Agriculture:</strong> Occasionally applied as a fungicide for crop protection against specific pathogens.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly requires prescription due to nephrotoxicity risks. Store at controlled room temperature (20-25°C) in a dry, light-resistant environment. Personnel must wear appropriate PPE during handling to avoid inhalation or skin contact.</p>