*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Amlodipine Besylate is a synthetic <strong>dihydropyridine calcium channel blocker</strong> widely manufactured via condensation of 2-amino-6-methyl-4-(2,4-dichlorophenyl)-5-pyridinecarboxylic acid ethyl ester with methyl acetoacetate. Its molecular formula is <strong>C<sub>20</sub>H<sub>25</sub>ClN<sub>2</sub>O<sub>5</sub>S</strong>, and CAS number is <strong>88150-42-9</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing</strong>: Primary API for treating hypertension and chronic stable angina.</li>
<li><strong>Cardiovascular Therapeutics</strong>: Used in fixed-dose combination tablets with ACE inhibitors or diuretics.</li>
<li><strong>Generic Drug Production</strong>: Key ingredient in cost-effective antihypertensive formulations globally.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly avoid use in patients with severe hypotension or obstructive aortic stenosis. Store in tightly sealed containers at controlled room temperature (20°C–25°C) away from moisture to prevent hydrolysis of the besylate salt.</p>