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<h3>Overview</h3>
<p><strong>Aminophylline</strong> (CAS: 49746-06-7) is a bronchodilator complex of theophylline and ethylenediamine. The core synthesis involves reacting anhydrous theophylline with ethylenediamine in ethanol to enhance water solubility. Molecular formula: C16H24N10O4.</p>
<h3>Application</h3>
<ul>
<li>Respiratory Therapeutics: Management of acute asthma exacerbations and COPD symptoms via intravenous or oral administration.</li>
<li>Apnea of Prematurity: Treatment for respiratory depression in neonates within intensive care units.</li>
<li>Diagnostics: Utilized as a standard reference material in pharmaceutical quality control assays.</li>
</ul>
<h3>Precautions</h3>
<p>Strict therapeutic monitoring required due to narrow safety index; contraindicated in active peptic ulcers. Store in tightly sealed, light-resistant containers at controlled room temperature (15-25°C) to prevent degradation.</p>