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Preclinical Research Services
CAS NO:
77479-02-8
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ChP,
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Basic Info
CAS Number
77479-02-8
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Aminolevulinic acid (ALA), chemically known as 5-aminolevulinic acid, is a pivotal non-protein amino acid and a crucial intermediate in the heme biosynthesis pathway. Its molecular formula is C5H9NO3, and it carries the CAS registry number 106-60-5. Naturally occurring in plants, animals, and bacteria, ALA serves as the primary precursor for the synthesis of porphyrins, which are essential components of hemoglobin, chlorophyll, and various cytochromes involved in cellular respiration and photosynthesis. In industrial and medical contexts, synthetic ALA has gained significant attention due to its unique photophysical properties.
The most prominent application of ALA lies in the field of dermatology and oncology as a photosensitizer precursor. When applied topically or administered systemically, ALA is taken up by rapidly dividing cells, such as tumor cells or abnormal skin lesions. Inside these cells, it is converted into protoporphyrin IX (PpIX). Upon exposure to specific wavelengths of light, PpIX generates reactive oxygen species that induce localized cell death. This mechanism forms the basis of Photodynamic Therapy (PDT), an effective treatment modality for actinic keratosis, basal cell carcinoma, and certain superficial tumors, offering a minimally invasive alternative with high cosmetic outcomes.
Beyond medicine, ALA is widely utilized in agriculture as a plant growth regulator. It enhances chlorophyll synthesis, thereby improving photosynthetic efficiency and crop yield under stress conditions. Additionally, it plays a role in food preservation by inhibiting microbial growth. In chemical research, ALA acts as a versatile building block for synthesizing complex heterocyclic compounds and pharmaceutical intermediates. Its ability to accumulate selectively in diseased tissues makes it invaluable for diagnostic imaging alongside therapeutic applications. As research advances, the scope of ALA usage continues to expand, highlighting its importance across diverse scientific disciplines ranging from biochemistry to clinical medicine.
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